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. 2021 Jun 4;9:642948. doi: 10.3389/fcell.2021.642948

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Copyright © 2021 He, Han, Li, Qian and Hou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential expression of genes in intestinal tumor tissues. (A) Hierarchical clustering analysis was performed according to the FPKM of each sample. (B) Volcano plot of DEGs in MSC group compared with AOM/DSS group. (C) KEGG enrichment analysis was conducted for downregulated genes in MSC group compared with AOM/DSS group. (D) Genes in the three top signaling pathways. (E–G) Expression of TNF-α, IL-1β, and IL-6 in serum was detected by enzyme-linked immune sorbent assay. *P < 0.05, **P < 0.01, ***P < 0.001. n = 3 mice per group.