Table 1.
Effect of BSO in models of LPS-induced inflammatory cytokines.
| Model | Result | Ref | Year |
|---|---|---|---|
| vivo mice | TNF ↑ | [29] | 1992 |
| vitro U373 astrocytoma | IL-8 ↑ | [118] | 1997 |
| vivo mice | TNF ≈ | [119] | 1999 |
| vitro alveolar macrophages | TNF, IL-8 ↑ | [120] | 1999 |
| vivo mice | TNF ↓ | [121] | 1999 |
| vitro THP1 monocytic cells | IL-12 ↓ | [122] | 2001 |
| vitro epitelial cells | TNF ↑ | [123] a | 2002 |
| vitro epitelial cells | TNF ↑ | [124] a | 2002 |
| vitro epitelial cells | TNF, IL-1β, IL-6 ↑ | [125] a | 2002 |
| vitro epitelial cells | TNF, IL-1β, IL-6 ↑ | [126] a | 2002 |
| vitro epitelial cells | TNF, IL-1β, IL-6 ↑ | [127] a | 2002 |
| vitro U937 monocytic cells | TNF ↑ | [128] | 2005 |
| vitro THP1 monocytic cells | TNF ≈ | [129] | 2008 |
| vitro epithelial cells | TNF ↑ | [130] | 2008 |
| ex vivo mouse peritoneal macrophages | IL-6 ↓ | [131] | 2009 |
| vitro epithelial cells | TNF ↑ | [132] a | 2011 |
| vitro dendritic cells | IL-12, IL-27 ↓ | [133] | 2011 |
| vitro RAW264 macrophages | IL-1β ↓ | [134] | 2017 |
| vitro RAW264 macrophages | TNF ≈, IL-1β ↓ | [61] | 2017 |
| vivo rat | IL-1β, IL-6, fever ↓ | [135] | 2017 |
| vitro RAW264 macrophages | TNF ≈ | [136] | 2018 |
| vitro RAW264 macrophages | IL-1β, IL-6 ≈ | [62] | 2018 |
| vitro RAW264 macrophages | TNF ↓ | [137] | 2021 |
↑, increase; ↓ decrease; ≈ no effect.
a
These different publications report results from the same experiment and should not be considered replications of published data.