Table 2.
Weight status and metabolic markers of the patients at baseline and week 8 (n = 44)
| Variable | Baseline | Week 8 | P |
|---|---|---|---|
| Weight, kg | 69.09 ± 8.84 | 68.95 ± 8.95 | 0.36a |
| BMI, kg/m2 | 27.93 ± 3.34 | 27.88 ± 3.38 | 0.39a |
| NO, μM | 56.72 ± 25.67 | 64.84 ± 17.78 | 0.11a |
| FBG, mg/dl | 156.68 ± 39.26 | 143.15 ± 48.37 | 0.01a |
| HbA1c, % | 6.78 (0.96) | 6.44 (0.94) | < 0.01b |
| Insulin, micIU/ml | 7.95 ± 4.53 | 7.20 ± 4.18 | 0.59a |
| HOMA-IR, N | 2.91 (1.62) | 2.61 (1.92) | 0.26b |
| QUICKI, N | 0.34 (0.03) | 0.34 (0.04) | 0.44b |
| TAG, mg/dl | 140.40 ± 61.50 | 136.00 ± 55.00 | 0.56a |
| TC, mg/dl | 157.22 ± 36.92 | 150.20 ± 33.73 | 0.18a |
| LDL-c, mg/dl | 144.00 (40.31) | 136.20 (40.00) | 0.12b |
| HDL-c, mg/dl | 44.00 (7.46) | 44.00 (8.31) | 0.79b |
| ApoA1, mg/dl | 133.04 ± 19.52 | 128.06 ± 19.52 | 0.10a |
| ApoB100, mg/dl | 101.00 ± 32.28 | 92.75 ± 30.33 | 0.03a |
| ApoA1/ApoB100 | 1.43.00 (0.46) | 1.52 (0.51) | 0.04b |
| AST, U/L | 21.40 (8.18) | 19.56 (8.33) | 0.04b |
| ALT, U/L | 17.88 (9.77) | 14.18 (8.52) | < 0.01b |
| Hcy, μmol/L | 27.77 ± 9.26 | 19.89 ± 9.58 | < 0.001a |
| hs-CRP, mg/l | 2.50 (1.93) | 2.87 (1.76) | 0.17 b |
| TAC, μmol/L | 90.00 (28.00) | 195.00 (59.50) | < 0.001b |
| PON1, U/L | 200.57 (18.15) | 230.01 (14.96) | 0.57 b |
| SBP, mmHg | 12.21 ± 1.01 | 11.48 ± 1.59 | < 0.001a |
| DBP, mmHg | 8.02 (0.95) | 7.68 (0.47) | 0.02 b |
a Values are shown as mean ± SD; P value is based on Paired-Samples T test
b Values are shown as median (interquartile range); P value is based on Wilcoxon Signed Ranks test
BMI, body mass index; NO, nitric oxide; FBG, fasting blood glucose; TAG, triacylglycerol; TC, total cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase; Hcy, homocysteine; hs-CRP, high-sensitive C reactive protein; TAC, total antioxidant capacity; PON1, paraoxonase-1; SBP, systolic blood pressure; DBP, diastolic blood pressure