Table 2.
Effect of selenium supplementation on inflammatory markers in included studies
| Author, year | Outcome | Results | ||||
|---|---|---|---|---|---|---|
| Group | Mean change ± SD | significance | SMD | |||
| 1 | Asemi, 2015 | hs-CRP (ng/mL) |
I: -791.88 ± 2271.84 P: 500.55 ± 2563.34 |
Yes | -0.53 | |
| NO (mmol/L) |
I: 20.91 ± 65.32 P: 5.03 ± 51.68 |
No | 0.26 | |||
| 2 | Shargorodsky, 2010 | hs-CRP(mg/dl) |
I: -1.32 ± 2.8 P: -0.49 ± 1.4 |
No | -0.37 | |
| Homocysteine(μmol/l) |
I: -0.05 ± 2.83 P: 0.36 ± 3.2 |
No | -0.13 | |||
| Ur cathacholamines (mg/24 h) |
I: 3.76 ± 20 P: 2.46 ± 18 |
No | 0.07 | |||
| 3 | Ravn-Haren, 2007 | CRP |
I: 0.08 ± 1.15 P: -0.08 ± 0.65 |
No | 0.17 | |
| 4 | Alizadeh, 2012 | hs-CRP, mg/l |
I: 0 ± 1.45 P: -0.3 ± 1.64 |
No | 0.19 | |
| NOx, _mol/l |
I: -8 ± 58.6 P: 3.7 ± 32.5 |
Yes | -0.24 | |||
| 5 | Murer, 2014 | CRP,2 mg/L serum |
I: 5.52 ± 8.3 P: -1.9 ± 4.5 |
No | 1.11 | |
| 6 | Razavi, 2016 | hs-CRP (ng/ml) |
I: − 711.3 ± 1959.3 P: 193.5 ± 1117.4 |
Yes | -0.56 | |
| NO (μmol/l) |
I: 3.85 ± 13.37 P: 0.07 ± 23.38 |
No | 0.19 | |||
| 7 | Farrokhian, 2016 | hs-CRP (ng/ml) |
I: − 1 372.3 ± 2 318.8 P: − 99.8 ± 1 453.6 |
Yes | -0.76 | |
| NO (μmol/l) |
I: − 8.9 ± 16.7 P: − 4.3 ± 9.3 |
No | -0.34 | |||
I Intervention group, C Control group, hs-CRP, high-sensitivity C-reactive protein, CRP C-reactive protein, NO nitric oxide, SMD standardized mean difference