Table 1.
Patient demographics (n = 27).
| Sex, n (%) | |
| Male | 17 (63.0) |
| Female | 10 (37.0) |
| Age (years) | |
| Median | 35.0 |
| Range | 20–70 |
| Histology, n (%) | |
| Nodular sclerosis | 14 (51.9) |
| Mixed cellularity | 2 (7.4) |
| Classical, not-otherwise-specified | 11 (40.7) |
| Disease status, n (%) | |
| Relapsed | 13 (48.1) |
| Refractory | 14 (51.9) |
| ECOG Performance Status | |
| 0 | 20 (74.1) |
| 1 | 7 (25.9) |
| Relapse < 12 months after frontline therapy? | |
| Yes | 6 (22.2) |
| No | 7 (25.9) |
| Not applicable (refractory) | 14 (51.9) |
| Extra-nodal disease at relapse, n (%) | |
| Yes | 5 (18.5) |
| No | 7 (25.9) |
| Unknown | 1 (3.7) |
| Not applicable (refractory) | 14 (51.9) |
| B symptoms prior to ASCT, n (%) | |
| Yes | 5 (18.5) |
| No | 20 (74.1) |
| Unknown | 2 (7.4) |
| Result of Pre-transplant PET-CT, n (%) | |
| Positive | 9 (33.3) |
| Negative | 15 (55.6) |
| Not applicable (not performed) | 1 (3.7) |
| Unknown | 2 (7.4) |
| Response to Salvage Chemotherapy, n (%) | |
| PR | 8 (29.6) |
| CR | 19 (70.4) |
| Disease Status Following ASCT, n (%) | |
| SD | 1 (3.7) |
| PR | 2 (7.4) |
| CR | 24 (88.9) |
| Hematologic parameters at registration (median, range) | |
| ANC (x 103 cells/µL) | 3.3 (1.7 – 10.1) |
| Platelet count (cells/µL) | 166,000 (62,000 – 369,000) |
| Hemoglobin (g/dL) | 12.3 (7.7 – 14.7) |
Abbreviations: ANC – absolute neutrophil count; ASCT – autologous stem cell transplantation; CR – complete response; PET-CT – position emission tomography – computed tomography; PR – partial response. PET scans were classified as positive or negative per International Working Group Criteria (28, 33).