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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Antiviral Res. 2021 Apr 14;190:105077. doi: 10.1016/j.antiviral.2021.105077

Table 1.

Anti-HCMV activities of Sulfated GAGs

Structure HCMV Antivirala (EC50) Cytotoxicity (TC50)b Selectivity index (SI)c
BoSG 1.719 ± 1.028 > 400 232.7
LvSF 1.369 ± 0.477 > 400 292.1
IbSF 0.662 ± 0.450 > 400 603.6
IbFucCS 0.422 ± 0.349 > 400 947.5
Heparin 0.331 ± 0.106 > 400 1211.1
a

GFP-based assay

b

CellTiter-Glo® assay

a,b

μg/mL; means of three independent experiments ± standard deviations

c

SI = TC50/EC50 (TC50 = 400 for these calculations)