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Anti-Adenovirus activities of Sulfated GAGs
| Structure | Adenovirus Antivirala (EC50) | Cytotoxicity (TC50)b | Selectivity index (SI)c |
|---|---|---|---|
| BoSG | 1.738 ± 0.201 | > 400 | 230.1 |
| LvSF | 0.229 ± 0.129 | > 400 | 1742.4 |
| IbSF | 0.237 ± 0.116 | > 400 | 1685.6 |
| IbFucCS | 0.124 ± 0.034 | > 400 | 3238.9 |
| Heparin | 1.815 ± 0.719 | > 400 | 220.4 |
GFP-based assay
CellTiter-Glo® assay
μg/mL; means of three independent experiments ± standard deviations
SI = TC50/EC50 (TC50 = 400 for these calculations)
