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Estimated Pharmacokinetic Parameters of Axitinib in the PEC and Vitreous Humor After a Single Bilateral SC or Intravitreal Injection of Axitinib Suspension (1 mg/Eye) in New Zealand White Rabbits
| PEC | Vitreous Humor | |||
|---|---|---|---|---|
| SC | IVT | SC | IVT | |
| AUC(0-t) (µg·d/g) | 5208 | 471 | 19 | 6208 |
| C max (µg/g) | 799 | 124 | 3.67 | 1280 |
| T max (h) | 6 | 24 | 168 | 0.08 |
