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. 2021 Jun 17;28:47. doi: 10.1186/s12929-021-00745-3

Table 1.

Demographic characteristics of the study population

Variables Control POAG SOAG XFG P-value
Patients (n) 20 20 19 19
Number of eyes (n) 20 20 19 19
Gender (male: female) 5:15 13:7 13:6 12:7 0.0204*
Age (years)
 Mean ± SD 73.5 ± 7.1 71.2 ± 10.2 61.2 ± 14.8 75.6 ± 12.8  < .005†, ††††
 [range] 58–87 52–87 39–87 39–93
IOP (mmHg)
 Mean ± SD 13.6 ± 1.7 15.7 ± 4.0 22.4 ± 11.9 29.7 ± 9.3 < .001,  < .0001**†, †††
 [range] 10–16 8–25 7–52 13–48

POAG primary open angle glaucoma, SOAG secondary open angle glaucoma, XFG exfoliation glaucoma, IOP intraocular pressure, ATX autotaxin, TGFβ transforming growth factor beta

*Fisher's exact test; **Kruskall-Wallis test

Statistically significant difference between control and SOAG (Steel–Dwass test)

††Statistically significant difference between control and XFG (Steel–Dwass test)

†††Statistically significant difference between POAG and XFG (Steel–Dwass test)

††††Statistically significant difference between SOAG and XFG (Steel–Dwass test)