Table 5.
Gene Functional Classification Result (PANTHER 14.1) of over-expressed genes in LE cells from SNEB animals. Main pathways and ontology annotation groups enriched are shown (over-representation statistical test)
| PANTHER Classification | fold Enrichment | raw P value | genes |
|---|---|---|---|
| PANTHER GO-Slim Molecular Function | |||
| signaling receptor binding (GO:0005102) | 4.21 | 6.60E-03 | BMP2, SEMA6D, IGHV2, NDP, TAP |
| cytokine activity (GO:0005125) | 7.42 | 3.05E-02 | BMP2, NDP |
| steroid binding (GO:0005496) | 25.23 | 3.13E-03 | PAQR8, OSBPL6 |
| PANTHER GO-Slim Biological Process | |||
| response to steroid hormone (GO:0048545) | 37.97 | 2.79E-02 | PAQR8 |
| defense response to bacterium (GO:0042742) | 10.07 | 1.75E-02 | IGHV2, TAP |
| PANTHER pathways | |||
| Signaling by PDGF (R-BTA-186797) | 44.52 | 5.36E-05 | PTPN12, THBS4, CRK |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) (R-BTA-2142691) | 33.64 | 3.12E-02 | CYP4B1 |