Table 1.

A summary of the performance selected non-commercial Candida PCR studies

Patient population	Case/control	Sample type	PCR target gene	PCR range	Sensitivity (%)	Specificity (%)	Ref
Sepsis	10/115	Blood culture	18S rRNA	Pan-Candida C. albicans, C. parapsilosis, C. tropicalis, C. glabrata	>99	90	[24]
Surgical patients with intra-abdominal candidiasis	17/39	Sera or plasma	ITS1 or ITS2 of rRNA	C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. guilliermondii	Post-transfusion fluids = 25% Pre-transfusion fluids = 64%	91	[13]
ICU/sepsis	8/58	EDTA blood	18S rDNA	Fungiplex C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. dubliniensis	100	94	[25]
	5/58		16S rDNA	SeptiFast C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei	60	96
ICU	6/175	Serum	ITS1/2 rDNA	C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. guilliermondii	16	93	[18]
ICU	10/39	Serum	18S rDNA	Fungiplex C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. dubliniensis	44	87	[26]
ICU	31/233	Serum	ITS1/2 rDNA	C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. guilliermondii	84	33	[19]
Mammary candidosis	65/89	Breast milk	ITS2	C. albicans, C. dubliniensis, C. glabrata, C. krusei, C. lusitaniae, C. parapsilosis, C. tropicalis	67	21	[27]
Unavailable	82 patients	Whole blood	5.8S rDNA	Candida genus	100	98	[28]
ICU/peritonitis	23/161	Peritoneal fluid	Not Stated	C. albicans, C. glabrata, C. parapsilosis, C. krusei, C. tropicalis, C. guilliermondii, C. dubliniensis	94	Not provided	[29]
Haematology	11/61	Whole blood	18S rDNA	Candida genus	100	100	[30]
ICU	27/103	Sera	ITS1/ITS2 rDNA	C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. guilliermondii	96	97	[17]
ICU with IC	55/128	Plasma/serum	ITS1, ITS2	C. albicans, C. glabrata, C. krusei, C. tropicalis	80	70	[14]