Table 4.

Summary of the results of classifier (C) models

Missing baseline data	Model name	Training data (n)	CV/test	AUC	Overall accuracy (%)	Sens (%)	Spec (%)	OOP
None	CG	13 936	CV	0.89	81	77	83	0.42
			test	0.89	81	75	85	0.42
Genotype	CNG	56 717	CV	0.84	77	71	80	0.43
			test	0.84	76	71	79	0.43
Time on therapy	CG(−ToT)	19 080	CV	0.90	82	80	84	0.42
			test	0.90	82	80	83	0.42
Genotype/time on therapy	CNG(−ToT)	56 717	CV	0.83	76	71	80	0.44
			test	0.82	76	71	79	0.44
Genotype/CD4 count	CNG(−CD4)	62 940	CV	0.83	76	72	79	0.44
			test	0.82	75	73	77	0.44
Genotype/time on therapy/ CD4 count	CNG(−ToT −CD4)	50 270	CV	0.79	72	71	73	0.38
			test	0.78	72	74	70	0.38

CV, cross-validation; test, independent testing; sens, sensitivity; spec, specificity.