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. Author manuscript; available in PMC: 2021 Jun 18.
Published in final edited form as: J Pathol. 2019 Aug 28;249(4):435–446. doi: 10.1002/path.5330

Figure 5.

Figure 5.

T2D alters HSPC response to skin wounding in DB mice. (A) Experimental design, (B) percentage (of total BMC) of HSC-LT, (C) HSC-ST, (D) MPP2, (E) MPP3, (F) MPP4, (G) CMP, (H) GMP, and (I) MEP in the BM of DB and ND mice at different time points post-skin wounding. Mean±SD, n=5–6 mice for each time point for each strain. Data were compared between DB and ND groups over different time points using two-way ANOVA and over different time points in the same group using one-way ANOVA (Kruskal–Wallis test) in kinetic assays. Differences between groups were considered significant if p≤0.05. a, mean value significantly different from day 0 in ND; b, mean value significantly different from day 0 in DB; c, mean value significantly different between two strains at the same time point.