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. 2021 Jun 3;9:673451. doi: 10.3389/fpubh.2021.673451

Table 1.

MR results of the causal effect of EA on the risk of COVID-19 severity.

IVW method Weighted median method MR-Egger regression method Heterogeneity (IVW) MR-PRESSO global test
OR (95% CI) OR (95% CI) OR (95% CI) Intercept Cochran's Q
P-value P-value P-value P-value P-value P-value
0.540 (0.376–0.777) 0.484 (0.283–0.826) 0.353 (0.084–1.483) 0.006 261.9
P = 0.0009 P = 0.008 P = 0.156 P = 0.548 P = 0.102 P = 0.115

MR, Mendelian randomization; COVID-19, coronavirus disease 2019; EA, educational attainment; IVW, inverse variance weighted; OR, odds ratio; CI, confidence interval.