Table 2.

Key Target Product Profile Criteria for Candidate Products

Dosage form	SC or IM injection
	SC implant
Dose volume (injectable):	2–4 mL
Size (conventional implant):	∼4 cm long; outer diameter ∼2 mm
Alternative implant design:	Consistent with end user acceptability
Time to sustainable effective exposure:	24 h
Other key specifications/attributes:	Minimal drug burst after dosing
	No prolonged PK tail
	Scalable manufacturing
	Cost effective relative to existing PrEP products
	Administration/use consistent with comparable contraceptive products

IM, intramuscular; PrEP, preexposure prophylaxis; SC, subcutaneous.