Table 2.
Study Expectations and Previous HIV Cure-Related Research Experiences Among AIDS Clinical Trials Group A5345 Cohort A Respondents, by Intensively Monitored Antiretroviral Pause Status, n = 32
Question Pre-IMAP, n = 16 Post-IMAP, n = 16 | Yes n (%) | No n (%) | Don't know n (%) | Missing n (%) | p valuea |
---|---|---|---|---|---|
Are you generally interested in HIV cure research? | |||||
Pre-IMAP | 16 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | N/A |
Post-IMAP | 16 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | |
Have you previously participated in an HIV treatment study? | |||||
Pre-IMAP | 8 (50%) | 6 (38%) | 2 (13%) | 0 (0%) | .882 |
Post-IMAP | 6 (38%) | 8 (50%) | 2 (13%) | 0 (0%) | |
Have you previously participated in an HIV cure study? | |||||
Pre-IMAP | 5 (31%) | 9 (56%) | 2 (13%) | 0 (0%) | .272 |
Post-IMAP | 10 (63%) | 5 (31%) | 1 (6%) | 0 (0%) | |
Have you previously participated in a study that involved pausing your anti-HIV medications? | |||||
Pre-IMAP | 1 (6%) | 15 (94%) | 0 (0%) | 0 (0%) | 1.000 |
Post-IMAP | 1 (6%) | 15 (94%) | 0 (0%) | 0 (0%) | |
Were you satisfied with the informed consent process? | |||||
Pre-IMAP | 15 (94%) | 0 (0%) | 0 (0%) | 1 (6%) | 1.000 |
Post-IMAP | 15 (94%) | 1 (6%) | 0 (0%) | 0 (0%) | |
Are there any risks to you from participating in this study? | |||||
Pre-IMAP | 13 (81%) | 2 (13%) | 1 (6%) | 0 (0%) | 1.000 |
Post-IMAP | 13 (81%) | 3 (19%) | 0 (0%) | 0 (0%) | |
Do you have any concerns about HIV inside your body increasing if you stop your anti-HIV medications? | |||||
Pre-IMAP | 4 (25%) | 11 (69%) | 1 (6%) | 0 (0%) | .357 |
Post-IMAP | 8 (50%) | 7 (44%) | 1 (6%) | 0 (0%) | |
Are there any direct benefits to you from participating in this study? | |||||
Pre-IMAP | 8 (50%) | 6 (38%) | 2 (13%) | 0 (0%) | .408 |
Post-IMAP | 11 (69%) | 5 (31%) | 0 (0%) | 0 (0%) | |
Will you receive a health benefit from being in this study? | |||||
Pre-IMAP | 6 (38%) | 6 (38%) | 4 (25%) | 0 (0%) | .035 |
Post-IMAP | 1 (6%) | 13 (81%) | 2 (13%) | 0 (0%) |
Pre- and post-IMAP groups are independent samples.
Fisher's exact test p-value (missing excluded).
IMAP, intensively monitored antiretroviral pause; N/A, not applicable.