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. 2021 Jun 4;11:649029. doi: 10.3389/fonc.2021.649029

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Copyright © 2021 Cao, Li, He, Jin, Li, Chen, Xu, Sun, Xiong and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FHL3 is an independent risk factor in gastric cancer. (1) The expression level of FHL3 in gastric cancer and its adjacent tissues was analyzed in TCGA database, GTEx, and Beijing dataset (A–H); the results suggested that FHL3 is highly expressed in tumor tissues. (2) The relationship between FHL3 expression level and prognosis is performed by Kaplan–Meier analysis in TCGA, KM-plotter cohorts; the results suggested that FHL3 is a prognostic indicator in gastric cancer; FHL3 overexpression always means poor overall survival (I, J).