Table 4. Association Constants for Duplex Formation between Sequence-Complementary 3-mers Measured by ITC Titration Experiments in Toluene at 298 K^a.

complex	log K (M–1)	ΔG° (kJ mol–1)	ΔH° (kJ mol–1)	ΔS° (J K–1 mol–1)
AAA·DDD	5.2	–29.5	–57	–92
AAD·ADD	4.2	–23.9	–45	–71
ADA·DAD	4.3	–24.6	–50	–85

^aErrors based on repeat experiments are 0.1 in log K, 0.5 kJ mol^–1 in ΔG°, 5 kJ mol^–1 in ΔH°, and 20 J K^–1 mol^–1 in ΔS°.