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. 2021 Jun 18;16(6):e0252411. doi: 10.1371/journal.pone.0252411

Table 8. Symptoms, signs, and findings associated with progression to severe disease.

Multivariate stepwise regression for patients who did not have severe disease or die in the first day of hospitalization (n=223).a

Effect Odds Ratio 95% Wald Confidence Limits P-Values
Respiratory symptoms 7.008 1.442 34.070 0.0158*
Tachypnea 2.211 0.911 5.368 0.0796
Hypoxia 19.946 2.609 152.490 0.0039*
Hypotension 2.677 1.036 6.914 0.0420*
eGFR<60 1.974 0.937 4.162 0.0737
Elevated D-Dimer (Elevated vs Normal) 0.413 0.128 1.333 0.1392
Elevated D-Dimer (Missing vs Normal) 1.064 0.457 2.476 0.8861

aN = 223, Used in Regression = 218, Severe = 54, Non-Severe = 164; 5 observations were not used because of missing x-ray;

*p-value of <0.05