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. 2021 Jun 4;11:694594. doi: 10.3389/fonc.2021.694594

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Copyright © 2021 Han, Zhao, Lu, Yun, Yang, Lou, Su, Chen, Zhang, Jin, Li, Sun, Huang, Wang and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The lower expression of BDH1 predicts the worse prognosis for AML patients. (A, B) Shown are comparisons of BDH1 gene expression levels among AML patients of different cytogenetic-risk classifications in TCGA-LAML database (A) and GSE6891 database (B), and comparison of BDH1 gene expression among AML patients of different FAB subtypes in TCGA-LAML database (C) and GSE6891 database (D). The expression values were log2-transformed and mean centered. The P values were detected by t-test. (E, F) Kaplan-Meier survival curves of BDH1 in TCGA-LAML (left) (E) and GSE6891 (right) (F) database. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.