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. 2021 Jun 4;9:641603. doi: 10.3389/fcell.2021.641603

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Copyright © 2021 Yin, Peng, Lin, Wang, Li, Wang and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression levels of S100B and MAP2 detected in SNI using fluorescence in situ hybridization. (A) Fluorescence in situ hybridization indicated that the expression of MSTRG.24008.1 was significantly increased and that of S100B was significantly decreased in the SNI group compared with those in the Sham group; however, the expression of MSTRG.24008.1 was significantly decreased and that of S100B was significantly increased in the SNI group treated with the MSTRG.24008.1 siRNA compared with those in the SNI group. (B) Fluorescence in situ hybridization indicated that the expression of MSTRG.24008.1 was increased, and that of MAP2 was significantly decreased in the SNI group compared with those in the Sham group; however, the expression of MSTRG.24008.1 was significantly decreased and that of MAP2 was significantly increased in the SNI group treated with the MSTRG.24008.1 siRNA compared with those in the SNI group. Scale bar: 20 μm (A,B).