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. 2021 Jun 18;100(24):e26371. doi: 10.1097/MD.0000000000026371

Table 2.

Illness characteristics and common symptoms of 423 symptomatic outpatients with mild to moderate COVID-19 during the 4-week follow-up.

No. (%)
Characteristic/symptom Illness Onset (N = 423) Week 1 (n = 167) Week 2 (n = 156) Week 3 (n = 155) Week 4 (n = 166)
Able to perform all ADLs 306/389 (78.7) 139 (83.2) 118 (75.6) 124 (80.0) 108 (65.1)
Unable to perform all ADLs 83/389 (21.3) 24 (14.4) 25 (16.0) 10 (6.5) 8 (4.8)
Visited the ED 105 (24.8) 9 (5.4) 9 (5.8) 6 (3.9) 9 (5.4)
Illness resolved 0 (0) 2 (1.2) 12 (7.7) 21 (13.5) 48 (28.9)
Symptoms
 Fever 236 (55.8) 76 (45.5) 37 (23.7) 11 (7.1) 4 (2.4)
 Chills or rigors 22 (5.2) 42 (25.1) 11 (7.1) 8 (5.2) 2 (1.2)
 Malaise 22 (5.2) 14 (8.4) 16 (10.3) 11 (7.1) 1 (0.6)
 Arthralgia 38 (9.0) 8 (4.8) 6 (3.8) 0 (0) 0 (0)
 Myalgia 25 (5.9) 47 (28.1) 17 (10.9) 4 (2.6) 1 (0.6)
 Headache 63 (14.9) 49 (29.3) 46 (29.5) 32 (20.6) 13 (7.8)
 Fatigue 20 (4.7) 33 (19.8) 39 (25.0) 34 (21.9) 16 (9.6)
 Anosmia/dysosmia 84 (19.9) 33 (19.8) 45 (28.8) 28 (18.1) 19 (11.4)
 Aguesia/dysguesia 21 (5.0) 29 (17.4) 44 (28.2) 25 (16.1) 17 (10.2)
Upper respiratory symptoms
 Sore throat 92 (21.7) 14 (8.4) 7 (4.5) 0 (0) 4 (2.4)
 Rhinorrhea 49 (11.6) 1 (0.6) 3 (1.9) 2 (1.3) 0 (0)
 Nasal/sinus congestion 88 (20.8) 12 (7.2) 16 (10.3) 6 (3.9) 5 (3.0)
Lower respiratory symptoms
 Cough 117 (27.7) 98 (58.7) 72 (46.2) 58 (37.4) 25 (15.1)
 Chest pain 87 (20.6) 7 (4.2) 10 (6.4) 7 (4.5) 3 (1.8)
 Dyspnea 2 (0.5) 24 (14.4) 25 (16.0) 20 (12.9) 13 (7.8)
GI symptoms
 Anorexia 127 (30.0) 11 (6.6) 15 (9.6) 8 (5.2) 2 (1.2)
 Nausea 15 (3.5) 7 (4.2) 13 (8.3) 8 (5.2) 3 (1.8)
 Vomiting 58 (13.7) 1 (0.6) 6 (3.8) 1 (0.6) 0 (0)
 Diarrhea 11 (2.6) 16 (9.6) 18 (11.5) 8 (5.2) 4 (2.4)
Palpitations 165 (39.0) 2 (1.2) 1 (0.6) 0 (0) 3 (1.8)
Light-headedness 0 (0) 9 (5.4) 10 (6.4) 4 (2.6) 5 (3.0)
Syncope 11 (2.6) 0 (0) 1 (0.6) 0 (0) 0 (0)