Table 1.
Baseline characteristics of 265 HCC patients.
| Variables | Total cohort (n = 265) | ≤7 cm subgroup (n = 168) | >7 cm subgroup (n = 97) | P value (≤7 cm vs >7 cm) |
| Age (years)∗ | 51 (43–60) | 52 (41–60) | 51 (44–60) | 0.825 |
| Male gender† | 231 (87.2%) | 147 (87.5%) | 84 (86.6%) | 0.832 |
| Positive HBsAg† | 228 (86.0%) | 143 (85.1%) | 85 (87.6%) | 0.570 |
| Total bilirubin (μmol/L)∗ | 13.4 (9.8–18.3) | 13.3 (9.9–19.3) | 13.5 (9.6–17.9) | 0.749 |
| Albumin (g/L)∗ | 38.4 (35.6–41.2) | 39.1 (36.4–41.4) | 37.9 (34.2–40.0) | 0.010 |
| ALBI grade† | 0.036 | |||
| 1 | 147 (55.5%) | 85 (50.6%) | 62 (63.9%) | |
| 2 | 118 (44.5%) | 83 (49.4%) | 35 (36.1%) | |
| Prothrombin time (s)∗ | 13.2 (12.2–14.4) | 13.2 (12.1–14.3) | 13.2 (12.3–14.4) | 0.934 |
| Platelet count (×109/L)∗ | 151 (106–210) | 135 (93–188) | 195 (136–246) | <0.001 |
| Maximum tumor size (cm)∗ | 6.0 (3.5–9.0) | 4.0 (3.0–5.5) | 10.0 (8.0–14.0) | <0.001 |
| Serum AFP ≥ 400 ng/mL† | 90 (34.0%) | 46 (27.4%) | 44 (45.4%) | 0.003 |
| Operative time (min)∗ | 180 (140–210) | 170 (136–205) | 180 (155–223) | 0.015 |
| Blood loss (mL)∗ | 300 (100–500) | 200 (100–400) | 400 (200–1000) | <0.001 |
| Major hepatectomy† | 42 (15.8%) | 6 (3.6%) | 36 (37.1%) | <0.001 |
| Poor differentiation grade† | 80 (30.2%) | 42 (25.0%) | 38 (39.2%) | 0.015 |
| Survival time (mo)∗ | 43 (25–61) | 49 (37–62) | 26 (15–57) | <0.001 |