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. 2021 Jun 17;14(8):1028–1034. doi: 10.1016/j.jiph.2021.06.010

Table 2.

Symptoms and Initial Physical Examination Findings for Patients with SARS-CoV-2 in association with Critical Illness (N = 249).

Characteristics Critical Illness
p-value
Yes (f, %), Mean (SD) No (f, %), Mean (SD)
No 66 (26.5) 183(73.5)
Age (mean SD) years 49.33(16.57) 40.97(16.11) 0.001*
Gender 0.303
 Male 42 (63.6) 129(70.5)
 Female 24(36.4) 54(29.5)
Admission criteria
Temperature
 Febrile 22(33.3) 90(49.2) 0.027*
 Afebrile 44(66.7) 93(50.2)
Respiratory rate, (/mints)* 23.50(4.35) 20.11(3.66) 0.001*
Heart rate, b/mints 101.08(24.24) 94.44(15.39) 0.012*
Blood pressure (mmHg)
 Systolic (SBP) 129.80(24.12) 124(19.56) 0.097
 Diastolic (DBP) 79.31(15.84) 78.05(13.13) 0.531
Smoking status
Former/Current
18(27.3) 29(15.8) 0.042*
History of travel 18(27.3) 35(19.1) 0.166
Comorbidity^ 41 (62.1) 45 (24.6) 0.001*
 CKD# 4(2.2) 8(12.1) 0.003*
 CAD# 9(4.9) 9(13.6) 0.027*
 HTN 22(12) 27(40.9) 0.001*
 DM 25(13.7) 24(36.4) 0.001*
 COPD 16(8.7) 15(22.7) 0.003*
 Immunodeficiency# 8(4.4) 6(9.1) 0.209
Signs-symptoms
 Fever 36(54.5) 60(32.8) 0.002*
 Cough 25(37.9 37(20.2) 0.004*
 Abnormal cardiac rhythm# 5(7.6) 2(1.1) 0.015*
 Dyspnea 45(68.2) 35(19.1) 0.001*
 Sore throat 6(9.1) 12(6.6) 0.044*
 Myalgia# 1(1.5) 9(4.9) 0.299
 Headache# 2(3) 5(2.7) 1.000
 Productive cough# 6(9.1) 12(6.6) 0.579
 Nausea & vomiting# 3(4.5) 5(2.7) 0.440
 Diarrhoea# 5(7.6) 13(7.1) 1.000
 Unconsciousness# 05(7.6) 61(92.4) 0.015*

^Comorbidity (yes); CKD-Chronic kidney disease; CAD-Coronary artery disease, COPD- Chronic obstructive pulmonary disease; LAP- Lymphadenopathy; HTN- Hypertension; DM- Diabetes mellitus; Independent t-test for continuous data and Chi-square and/or (#) Fisher exact test for categorical variables; SD- standard deviation; * - Significant @ P < 0.05.