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. Author manuscript; available in PMC: 2021 Jun 18.
Published in final edited form as: Pediatr Res. 2020 Feb 13;88(4):546–555. doi: 10.1038/s41390-020-0797-6

Fig 2. Formula causes apoptosis and mild injury to immature intestine that is ameliorated by treatment with Lactobacillus rhamnosus GG (LGG).

Fig 2.

(A-B) Quantification of CC3 protein using densitometry demonstrated formula-induced increase in CC3 levels which were attenuated with LGG treatment in FP and FPP groups. (n≥5 per group; ***p<0.001). (C-D) Examination of terminal ileum of formula-fed pups shows damage to intestinal epithelial cells compared to controls which was partially decreased with LGG treatment. Quantification of intestinal injury by a validated scoring tool shows decrease in injury score following high-dose LGG (FPP), but not following low-dose LGG (FP). (n≥6 per group; ***p<0.001, **p<0.01).