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Hyperoside inhibits LPS-induced HT22 cell oxidative stress and reduction of neurotrophic factor through SIRT1. The level of SOD, GSH, CAT, ROS, and MDA were measured by corresponding assay kits (a). The expression of BDNF, TrkB, and NGF in HT22 cells was measured by western blotting (b). ∗ was considered significant compared to control (∗P < 0.05); # was considered significant compared to LPS (#P < 0.05); ▽ was considered significant compared to LPS + HYP (▽P < 0.05).
