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. 2021 Jun 18;28(10):5897–5905. doi: 10.1016/j.sjbs.2021.06.046

Table 2.

Established antiviral activities of probiotics and bioactive peptides present in yogurt.

Investigated probiotics and bioactive peptides Antiviral activity against Methodology References
Bioactive peptides produced by Lactobacillus delbrueckii WS4 SARS-CoV, SARS-CoV-2, MERS-CoV, HCoV-HKU1 In silico (Chourasia et al., 2020)
Bioactive peptides derived from beta-lactoglobulin SARS-CoV-2 In silico (Çakır et al., 2021)
Bioactive peptides derived from Lactobacillus plantarum and Bifidobacterium bifidum Enterovirus 71 In vitro (Choi et al., 2010)
Lactobacillus reuteri Protectis Coxsackievirus A, Enterovirus 71 In vitro (Ang et al., 2016)
Probiotic metabolites of Lactobacillus casei and Bifidobacterium adolescentis Rotavirus In vitro (Olaya Galán et al., 2016)
P18 peptide of Bacillus subtilis Influenza virus In vitro and in vivo (mice) (Starosila et al., 2017)
Lactobacillus gasseri SBT2055 Respiratory sentential virus In vivo (mice) (Eguchi et al., 2019)

SARS-CoV-2, severe acute respiratory syndrome coronavirus; MERS-CoV, Middle-East respiratory syndrome-related coronavirus; HCoV-HKU1, human coronavirus HKU1.