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. 2021 Jun 19;69(4):312–322. doi: 10.1007/s12026-021-09203-6

Fig. 2.

Fig. 2

ARNAX signaling pathway. ARNAX activates TLR3 but not cytoplasmic MDA5/RIG-I. The TLR3-TICAM-1-IRF3-IFNAR signaling axis is crucial in dendritic cells for ARNAX-mediated cytotoxic T lymphocyte (CTL) induction