Table 6.
MTA study characteristics
| Author (year) | Study design | Size | Tooth type | Age (y) mean | Aetiology | TG | Irrigant | DRE | DRE, weeks | RF material | Outcome | Follow -p, months | Drop- outs | Failure |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bucher (2016) | RECO | 98 |
A P M |
> 6 |
66.3% T 1% DC 7.1% RETR 7.1% MIH |
I = 98; C = 0 | 3% NaOCl; 24% EDTA; 2% CHX; 0.9% NaCl | CH/L | 1–4 | WMTA/GP |
97% functional retention; 94% clinical success; 71.4% optimal root filling; 3.1% failure; 90.2% AP-healing; 95% survival trauma; 70% survival non-trauma |
30 | N.S | n = 3 |
| Ree (2017) | RECO | 83 | A | 10.15 |
71% T 4% DA 25% RETR |
I = 20; C = 0 | 5% NaOCl; 17%EDTA | CH | 3–4 | CS/WMTA/GP/R/FP |
96% AP-healing 98.5% survival |
100 | n = 14 | n = 1 |
| Demiriz (2017) | RECO | 55 | A | 9.47 | NS |
I:MTA extrusion = 21 C:MTA no extrusion = 34 |
2.5%NaOCl | CH | N.S | GMTA |
100% survival 90,4% MTA extrusion complete AP-healing; 100% control group with no MTA extrusion complete AP-healing 89,5% reduced amount of extruded MTA in teeth with complete healing 10% extruded MTA absent after 3 years |
36 | n = 10 | N.S |
| Kandemir Demirci (2014) | RCT | 90 | A | 18–40; mean 23.34 |
T DC DA |
I(MTA) = 45; C(CH) = 45 |
2.5%NaOCl; 17% EDTA; 2% CHX |
CH |
MTA1;CH N.S |
WMTA/GP |
MTA: 92% survival; 8% failed; 74% apexification /AP-healing; 18% ongoing AP-healing, 8% no AP-healing CH: 91% AP-healing / 79% complete AP-healing; 12% apexification / ongoing AP-healing; 9% no AP-healing |
mean 32.3 | n = 17; (87% for MTA and 76% for CH) | n = 3 |
| Mente (2013) | RELCO | 221 |
A P M |
9–80 (median 43) | N.S | I = 252; C = 0 |
NaOCl EDTA |
CH | N.S: | WMTA/GP |
96% survival 90% AP-healing Prognostic factors: 2. Experience of TR-provider 3. Number of treatment sessions 4. MTA extrusion |
12–128 (median 21) | n = 27 | N.S |
RECO retrospective cohort study, RCT randomised clinical trial, RELCO retrospective longitudinal cohort study, A anterior, P premolar, M molar, T trauma, DC dental caries, DA dental anomalies, RETR endodontic retreatment cases, MIH hypofosfatasia, DRE root canal dressing, CH calcium hydroxide, CHX chloridehexidine gluconate, I intervention group, C control group, NS not stated, RF material root-filling material, WMTA white MTA Pro Root, GMTA grey MTA Angelus, GP gutta percha, CS calcium sulfate, R resilon, FP fiber post, L Corticosteroid Ledermix, TG treatment groups, AP healing-radiographic resolution of apical pathology, TR-provider treatment provider