Table 1.

Clinicopathological features of triple-negative breast cancer (TNBC) and the status of intratumoral and stromal CD20, CD38, and CD138 (N= 114)

Clinicopathological feature	Total no. of cases	iCD20			iCD38			iCD138			sCD20			sCD38			sCD138
		Low	High	P value*	Low	High	P value*	Low	High	P value*	Low	High	P value*	Low	High	P value*	Low	High	P value
Age (years)				0.209			0.053			0.349			0.574			0.574			0.432
<60	55	32	23		36	19		25	30		26	29		26	29		23	32
≥60	59	41	18		28	31		32	27		31	28		31	28		29	30
Tumor size (cm)				0.536			0.221			0.562			0.176			0.344			0.311
≤2	71	47	24		43	28		34	37		32	39		38	33		35	36
>2	43	26	17		21	22		23	20		25	18		19	24		17	26
Histological grade				0.052			0.580			0.155			0.542			0.310			0.100
I and II	35	27	8		21	14		14	21		19	16		20	15		20	15
III	79	46	33		43	36		43	36		38	41		37	42		32	47
Histology				0.132			0.111			0.258			0.899			0.258			0.992
IDC	88	56	32		45	43		45	43		13	45		43	45		40	48
ILC	2	0	2		1	1		2	0		1	1		0	2		1	1
Other types	24	17	7		18	6		10	14		13	11		14	10		11	13
Mib-1				0.199			0.918			0.469			0.469			0.227			0.032*
<20%	21	16	5		12	9		9	12		12	9		13	8		14	7
≥20%	93	57	36		52	41		48	45		45	48		44	49		38	55
iTILs				0.002*			0.868			0.454			0.009*			0.143			0.561
Low	58	45	13		33	25		31	27		36	22		33	25		28	30
High	56	28	28		31	25		26	30		21	35		24	32		24	32
sTILs				0.004*			0.406			1.000			<0.001*			<0.001*			0.011*
Low	62	47	15		37	25		31	31		47	15		44	18		35	27
High	52	26	26		27	25		26	26		10	42		13	39		17	35
TLS				0.008*			0.540			0.023*			<0.001*			0.148			0.036*
Absent	81	58	23		44	37		46	35		51	30		44	37		42	39
Present	33	15	18		20	13		11	22		6	27		13	20		10	23

TNBC triple-negative breast cancer, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, TLS tertiary lymphoid structures, i intratumoral, s stromal, TILs Tumor-infiltrating lymphocytes

*p value is significant, χ² test