Table 2.

Logistic regression on role of butyrate-producing bacteria on stroke outcome

	Univariate		Multivariate
	Odds ratio (2.5–97.5%)	p value	Odds ratio (2.5–97.5%)	p value
Clinical infection
Age	1.04 [1.00–1.09]	0.10
Male sex	1.07 [0.36–3.31]	0.905
Diabetes	1.73 [0.46–5.35]	0.369
Prior stroke	0.88 [0.24–2.69]	0.827
NIHSS > 10	3.65 [1.21–11.00]	0.019	3.07 [0.94–9.87]	0.058
Butyrate-producing bacteria (log abundance)	0.74 [0.61–0.90]	0.001	0.74 [0.60–0.91]	0.005
Ceftriaxone exposure	0.21 [0.05–0.67]	0.017	0.16 [0.03–0.56]	0.009
90-day mortality
Age	1.07 [1.04–1.11]	<0.001	1.06 [1.03–1.10]	<0.001
Male sex	0.59 [0.30–1.13]	0.112
Diabetes	1.65 [0.75–3.41]	0.190
Prior stroke	1.31 [0.65–2.57]	0.432
NIHSS > 10	8.34 [4.19–17.17]	<0.001	8.27 [4.03–17.52]	<0.001
Butyrate-producing bacteria (log abundance)	0.91 [0.79–1.06]	0.204
Ceftriaxone exposure	0.21 [0.05–0.67]	0.160
Unfavorable outcome*
Age	1.04 [1.02–1.06]	< 0.001	1.04 [1.02–1.06]	< 0.001
Male sex	0.47 [0.23–0.73]	<0.001	0.67 [0.40 – 1.12]	0.129
Diabetes	1.77 [1.03–3.04]	0.038	2.15 [1.14 – 3.76]	0.016
Prior stroke	1.49 [0.93–2.37]	0.093
NIHSS > 10	9.38 [5.32–1 .20]	< 0.001	9.88 [5.32–19.20]	< 0.001
Butyrate-producing bacteria (log abundance)	0.88 [0.78–0.98]	0.043	0.89 [0.7–1.02]	0.266
Ceftriaxone exposure	1.15 [0.60–2.27]	0.675