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. 2021 Jun 18;12:3781. doi: 10.1038/s41467-021-23977-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A–D Scatterplot of baseline IgG levels for HKU1, OC43 and 229E S protein; and HKU1 S1 and fold induction of SARS-CoV-2 antibodies: neutralizing (nAb), IgG spike, IgG RBD, IgM spike, and nucleoprotein. Overlay shows relationship with induction of de novo antibodies against SARS-CoV-2 at each time point. Fitted linear regression and standardized beta coefficient (95% Confidence Interval, CI) for significant linear regressions are shown. Reported p values are based on two‐tailed tests.