Table 2.
Characteristics of male subjects divided by tertiles of FLI at baseline (n = 7925).
| T1 (0.9–21.8) | T2 (21.9–49.7) | T3 (49.8–99.7) | P | |
|---|---|---|---|---|
| n = 2650 | n = 2633 | n = 2642 | ||
| Age (years) | 47 ± 11 | 49 ± 9 | 48 ± 9 | < 0.001 |
| Body mass index | 21.4 ± 1.9 | 23.9 ± 1.9 | 26.6 ± 3.0 | < 0.001 |
| Waist circumference (cm) | 78.7 ± 5.3 | 86.1 ± 4.9 | 93.1 ± 7.0 | < 0.001 |
| Systolic blood pressure (mmHg) | 115 ± 15 | 120 ± 15 | 125 ± 15 | < 0.001 |
| Diastolic blood pressure (mmHg) | 73 ± 10 | 77 ± 10 | 81 ± 10 | < 0.001 |
| Smoking habit | 1139 (44.3) | 1121 (43.5) | 1219 (47.5) | 0.007 |
| Alcohol drinking habit | 1011 (37.6) | 1189 (44.2) | 1271 (47.4) | < 0.001 |
| Family history | ||||
| Diabetes mellitus | 372 (14.0) | 405 (15.3) | 443 (16.8) | 0.023 |
| Comorbidity | ||||
| Hypertension | 152 (5.7) | 299 (11.1) | 447 (16.7) | < 0.001 |
| Dyslipidemia | 39 (1.5) | 113 (4.2) | 176 (6.6) | < 0.001 |
| Biochemical data | ||||
| Albumin (g/dL) | 4.4 ± 0.2 | 4.4 ± 0.2 | 4.5 ± 0.2 | < 0.001 |
| eGFR (mL/min/1.73 m2) | 85.1 ± 14.0 | 82.3 ± 13.9 | 82.6 ± 14.1 | < 0.001 |
| Uric acid (mg/dL) | 5.7 ± 1.1 | 6.1 ± 1.2 | 6.6 ± 1.2 | < 0.001 |
| FPG (mg/dL) | 89 ± 9 | 92 ± 9 | 95 ± 12 | < 0.001 |
| Hemoglobin A1c (%) | 5.1 ± 0.4 | 5.3 ± 0.4 | 5.4 ± 0.4 | < 0.001 |
| AST (U/L) | 21 (17–23) | 24 (19–26) | 31 (22–34) | < 0.001 |
| ALT (U/L) | 20 (15–24) | 28 (19–33) | 45 (27–53) | < 0.001 |
| γGTP (U/L) | 30 (20–34) | 53 (30–61) | 108 (51–125) | < 0.001 |
| Total cholesterol (mg/dL) | 194 ± 30 | 206 ± 32 | 216 ± 35 | < 0.001 |
| LDL cholesterol (mg/dL) | 116 ± 28 | 126 ± 30 | 126 ± 33 | < 0.001 |
| HDL cholesterol (mg/dL) | 62 ± 15 | 56 ± 14 | 51 ± 12 | < 0.001 |
| Non-HDL cholesterol (mg/dL) | 132 ± 30 | 150 ± 32 | 165 ± 35 | < 0.001 |
| Triglycerides (mg/dL) | 78 (58–94) | 120 (87–144) | 197 (125–230) | < 0.001 |
Variables are expressed as number (%), means ± SD or medians (interquartile ranges).
AST aspartate aminotransferase, ALT alanine aminotransferase, eGFR estimated glomerular filtration rate, FLI fatty liver index, FPG fasting plasma glucose, γGTP γ-glutamyl transferase, HDL high-density lipoprotein, LDL low-density lipoprotein.