Table 3.
Characteristics of female subjects divided by tertiles of FLI at baseline (n = 4365).
| T1 (0.4–4.4) | T2 (4.5–12.6) | T3 (12.7–97.4) | P | |
|---|---|---|---|---|
| n = 1458 | n = 1455 | n = 1452 | ||
| Age (years) | 43 ± 9 | 48 ± 9 | 51 ± 10 | < 0.001 |
| Body mass index | 19.2 ± 1.5 | 21.2 ± 1.7 | 24.8 ± 3.3 | < 0.001 |
| Waist circumference (cm) | 70.9 ± 4.7 | 78.0 ± 4.8 | 87.7 ± 7.9 | < 0.001 |
| Systolic blood pressure (mmHg) | 105 ± 13 | 110 ± 16 | 118 ± 16 | < 0.001 |
| Diastolic blood pressure (mmHg) | 66 ± 9 | 69 ± 10 | 75 ± 10 | < 0.001 |
| Smoking habit | 263 (18.6) | 254 (17.9) | 285 (20.2) | 0.219 |
| Alcohol drinking habit | 211 (14.5) | 257 (17.5) | 261 (17.8) | 0.001 |
| Family history | ||||
| Diabetes mellitus | 272 (18.7) | 292 (20.0) | 331 (22.8) | 0.020 |
| Comorbidity | ||||
| Hypertension | 28 (1.9) | 76 (5.2) | 216 (14.8) | < 0.001 |
| Dyslipidemia | 21 (1.4) | 53 (3.6) | 105 (7.2) | < 0.001 |
| Biochemical data | ||||
| Albumin (g/dL) | 4.3 ± 0.2 | 4.3 ± 0.2 | 4.3 ± 0.2 | 0.234 |
| eGFR (mL/min/1.73 m2) | 89.1 ± 15.1 | 85.9 ± 15.3 | 85.0 ± 15.6 | < 0.001 |
| Uric acid (mg/dL) | 4.1 ± 0.8 | 4.3 ± 0.9 | 4.8 ± 1.0 | < 0.001 |
| FPG (mg/dL) | 83 ± 7 | 86 ± 8 | 90 ± 9 | < 0.001 |
| Hemoglobin A1c (%) | 5.1 ± 0.3 | 5.2 ± 0.3 | 5.3 ± 0.4 | < 0.001 |
| AST (U/L) | 19 (16–20) | 20 (16–22) | 22 (18–24) | < 0.001 |
| ALT (U/L) | 14 (11–16) | 16 (12–18) | 23 (15–27) | < 0.001 |
| γGTP (U/L) | 16 (12–18) | 21 (14–23) | 41 (19–44) | < 0.001 |
| Total cholesterol (mg/dL) | 191 ± 31 | 205 ± 32 | 216 ± 33 | < 0.001 |
| LDL cholesterol (mg/dL) | 106 ± 26 | 120 ± 30 | 131 ± 31 | < 0.001 |
| HDL cholesterol (mg/dL) | 75 ± 14 | 70 ± 14 | 63 ± 14 | < 0.001 |
| Non-HDL cholesterol (mg/dL) | 117 ± 27 | 134 ± 31 | 154 ± 34 | < 0.001 |
| Triglycerides (mg/dL) | 49 (40–60) | 68 (54–85) | 100 (76–134) | < 0.001 |
Variables are expressed as number (%), means ± SD or medians (interquartile ranges).
AST aspartate aminotransferase, ALT alanine aminotransferase, eGFR estimated glomerular filtration rate, FLI fatty liver index, FPG fasting plasma glucose, γGTP γ-glutamyl transferase, HDL high-density lipoprotein, LDL low-density lipoprotein.