Table 1.
Descriptive statistics on 6-month EPIC-CP symptoms by treatment choice
| Definitive treatment type |
||||||
|---|---|---|---|---|---|---|
| Total (n=257) | Active Surv (n=76) | Definitive Tx (n=181) | Other (n=2) | Radiation (n=77) | Surgery (n=102) | |
| Urinary incontinence | ||||||
| Median (IQR) | 2.0 (0.0 - 4.0) | 1.0 (0.0 - 2.0)* | 2.0 (1.0 - 5.0) | - | 1.0 (0.0 - 2.0) | 4.0 (2.0 - 7.0)+ |
| 0 | 75 (29.2%) | 35 (46.1%) | 40 (22.1%) | 0 (0.0%) | 33 (42.9%) | 7 (6.9%) |
| >0 | 172 (66.9%) | 37 (48.7%) | 135 (74.6%) | 2 (100.0%) | 42 (54.5%) | 91 (89.2%) |
| Missing | 10 (3.9%) | 4 (5.3%) | 6 (3.3%) | 0 (0.0%) | 2 (2.6%) | 4 (3.9%) |
| Urinary irritation | ||||||
| Median (IQR) | 3.0 (1.0 - 5.0) | 2.0 (0.2 - 4.0) | 3.0 (1.0 - 5.0) | - | 4.0 (2.0 - 6.0)~ | 2.0 (1.0 - 4.0) |
| 0 | 44 (17.1%) | 18 (23.7%) | 26 (14.4%) | 1 (50.0%) | 9 (11.7%) | 16 (15.7%) |
| >0 | 200 (77.8%) | 52 (68.4%) | 148 (81.8%) | 1 (50.0%) | 67 (87.0%) | 80 (78.4%) |
| Missing | 13 (5.1%) | 6 (7.9%) | 7 (3.9%) | 0 (0.0%) | 1 (1.3%) | 6 (5.9%) |
| Hormonal | ||||||
| Median (IQR) | 1.0 (0.0 - 4.0) | 1.0 (0.0 - 3.0) | 2.0 (0.0 - 4.0) | - | 3.0 (1.0 - 5.0)~ | 1.0 (0.0 - 3.0) |
| 0 | 82 (31.9%) | 26 (34.2%) | 56 (30.9%) | 2 (100.0%) | 12 (15.6%) | 42 (41.2%) |
| >0 | 159 (61.9%) | 44 (57.9%) | 115 (63.5%) | 0 (0.0%) | 62 (80.5%) | 53 (52.0%) |
| Missing | 16 (6.2%) | 6 (7.9%) | 10 (5.5%) | 0 (0.0%) | 3 (3.9%) | 7 (6.9%) |
| Bowel | ||||||
| Median (IQR) | 0.0 (0.0 - 2.0) | 0.0 (0.0 - 1.0)* | 0.0 (0.0 - 3.0) | - | 1.0 (0.0 - 4.0) | 0.0 (0.0 - 2.0) |
| 0 | 145 (56.4%) | 52 (68.4%) | 93 (51.4%) | 2 (100.0%) | 36 (46.8%) | 55 (53.9%) |
| >0 | 104 (40.5%) | 21 (27.6%) | 83 (45.9%) | 0 (0.0%) | 40 (51.9%) | 43 (42.2%) |
| Missing | 8 (3.1%) | 3 (3.9%) | 5 (2.8%) | 0 (0.0%) | 1 (1.3%) | 4 (3.9%) |
| Sexual | ||||||
| Median (IQR) | 6.0 (3.0 - 9.0) | 3.0 (1.0 - 5.0)* | 8.0 (5.0 - 10.0) | - | 6.0 (3.8 - 8.0) | 8.0 (6.0 - 10.0)+ |
| 0 | 19 (7.4%) | 14 (18.4%) | 5 (2.8%) | 0 (0.0%) | 4 (5.2%) | 1 (1.0%) |
| >0 | 219 (85.2%) | 55 (72.4%) | 164 (90.6%) | 2 (100.0%) | 68 (88.3%) | 94 (92.2%) |
| Missing | 19 (7.4%) | 7 (9.2%) | 12 (6.6%) | 0 (0.0%) | 5 (6.5%) | 7 (6.9%) |
Note: EPIC-CP=Expanded Prostate Cancer Index Composite-Clinical Practice; Surv=Surveillance; Tx=Treatment IQR=Interquartile range
*
Significantly different between active surveillance and active treatments
+
Surgery significantly worse than radiation
~
Radiation significantly worse than surgery