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. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: Biol Psychiatry. 2020 Dec 19;90(2):102–108. doi: 10.1016/j.biopsych.2020.12.011

Figure 1: Sex specificity in postmortem transcriptomes of MDD and PTSD.

Figure 1:

Divergent profiles were observed between male and female transcriptomes in MDD and PTSD. Comparative analysis of MDD and PTSD revealed sparse overlap in transcriptome profiles despite high incidence of MDD in PTSD diagnoses. Animal model studies of genes dysregulated in male or female MDD exhibit depressive-like behavior only in animals of the matching and not the opposite sex.