Table 9. The effect of CDSS on medication adherence and Drug-drug interactions (DDIs) .

References	CDSS focus ( study objective)	Effect measures	Main findings
(102)	Assessing the most effective factors that influence patients’ adherence to medication therapy in patients with osteoporosis	Patient adherence to drugs improved	Findings indicated that factors such as making dosing regimen simpler, patient decision making support system, patient education, and electronic prescription system were most effective in patients’ drug adherence in patients with osteoporosis. However, the patient decision making support system was the most effective factor.
(13)	Evaluating the effects and characteristics of computerized interventions on the outcomes of DDI	Increasing DDI alert adherence and clinical outcomes with computerized interventions	The results showed that DDI alert adherence and clinical outcomes were increased by computerized interventions. The effect of DDI on the medication-related issues such as drug prescription, administration, and dispense at decision making time