Table 4. The pooled ORs and 95% CIs for the association between IL1-β polymorphisms and overall risk of gestational disorders .

			Association test		Heterogeneity			Egger's test
Polymorphism	No	Genetic model	OR (95% CI)	p	Model	p	I2 (%)	p
IL‐1β −511C>T	11	C vs. T	1.07 (0.91-1.26)	0.39	Random	0.0001	70.44%	0.0002
	11	CT vs. TT	0.90 (0.78-1.04)	0.14	Fixed	0.32	31.32%	0.15
	11	CC vs. TT	1.15 (0.85-1.58)	0.39	Random	0.00	68.03%	0.0005
	11	CT+CC vs. TT	1.00 (0.80-1.25)	0.98	Random	0.03	57.88%	0.008
	11	CC vs. CT+TT	1.18 (0.95-1.46)	0.12	Random	0.0004	56.10%	0.011
IL‐1β −31T>C	5	T vs. C	0.89 (0.71-1.11)	0.31	Random	0.04	60.10%	0.12
	5	CT vs. CC	0.74 (0.59-0.92)	0.01	Fixed	0.30	17.30%	0.01
	5	TT vs. CC	0.80 (0.54-1.20)	0.28	Random	0.08	51.94%	0.23
	5	CT+TT vs. CC	0.74 (0.60-0.91)	0.01	Fixed	0.13	44.41%	0.02
	5	TT vs. CT+CC	0.92 (0.73-1.15)	0.47	Fixed	0.16	39.31%	0.64
IL- β +3954C>T	5	T vs. C	1.44 (0.75-2.77)	0.27	Random	0.0001	93.35%	0.88
	5	CT vs. CC	1.79 (0.82-3.91)	0.14	Random	0.0001	90.95%	0.17
	3	TT vs. CC	3.37 (0.46-24.88)	0.23	Random	0.0001	91.53%	0.72
	5	CT+TT vs. CC	1.82 (0.84-3.95)	0.13	Random	0.0001	91.18%	0.16
	3	TT vs. CT+CC	1.83 (0.86-3.90)	0.12	Random	0.07	63.05%	0.54

P<0.05 is considered as statistically significant (bolded P-value).