Table 4.
Overlapping coefficient, standardized overlapping coefficient, nominal number of patients to be borrowed, and power parameter (or exponent) in each stratum for arm A
| PS stratum | Total | |||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | ||
| Current study (n) | 80 | 80 | 80 | 80 | 80 | 400 |
| EU registry (n) | 269 | 218 | 160 | 196 | 98 | 941 |
| Overlapping coefficient | 0.79 | 0.79 | 0.83 | 0.84 | 0.90 | |
| Standardized overlapping coefficient (%) | 19 | 19 | 20 | 20 | 22 | 100 |
| Patients borrowed (= 100 × Std. Overlap. Coef.) | 19 | 19 | 20 | 20 | 22 | 100 |
| α (or λ) [= Patients Borrowed/EU registry (n)] | 0.07 | 0.09 | 0.13 | 0.10 | 0.22 | |