Panel A. EEG of tonic seizure on day of presentation showing brief 1–2 second burst of generalized 6–7 Hz activity, followed by several seconds of diffuse attenuation with superimposed fast activity and myogenic artifact that evolves into 2 Hz generalized rhythmic activity. Panel B. Breakthrough tonic seizures after 1 week of treatment for SRSE: gradual buildup of low voltage fast activity over 15–20 seconds, often followed by generalized slow wave and diffuse attenuation. Panel C. Interictal EEG one month into hospitalization showing generalized epileptiform discharges. In addition to multifocal epileptiform discharges, most frequent over the left temporal region. All EEGs displayed at 7 uV/mm, HFF 70 Hz, LFF 1 Hz.