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. 2021 May 20;297(1):100806. doi: 10.1016/j.jbc.2021.100806

Figure 2.

Figure 2

Intracellular polyols did not affect the TRPV1 heat activation.A, representative macroscopic current traces recorded from TRPV1 channels after applying different polyols from the intracellular side. B, intracellularly perfused polyols did not change thermal activation threshold of wildtype TRPV1 at both concentrations of sorbitol (n = 4). C and D, the relationship between the thermal activation threshold of wildtype TRPV1 and the concentration of polyols or hydroxyl groups (n = 3–10). The data are represented as the mean ± SD. Statistical analyses were performed by one-way ANOVA with Dunnett’s multiple comparisons post hoc test. n.s., not significant.