Table 3.
Distribution of Exhaled NO Metrics Within 3 OSA Severity Sub-Groups
| Parameters | Mild OSA (n=17) | Moderate OSA (n=23) | Severe OSA (n=83) | p-value |
|---|---|---|---|---|
| FENO 50 mL/s (ppb) | 10.64 (5.55–24.91) | 13.37 (5.84–28.56) | 13.52 (6.12–24.69) | 0.4764 |
| FENO 100 mL/s (ppb) | 11.98 (7.10–22.90) | 15.49 (6.35–27.46) | 12.11 (4.83–21.17) | 0.1100 |
| FENO 150 mL/s (ppb) | 9.8 (4.41–16.6) | 13.1 (4.85–23.90) | 10.0 (4.62–20.49) | 0.0759 |
| FENO 350 mL/s (ppb) | 8.14 (3.68–10.33) | 9.11 (5.54–17.87) | 7.02 (2.70–14.08) | 0.1694 |
| J’AWNO (nl/min) | 11.2 (1.88–55.52) | 33.9 (1.65–71.84) | 36.2 (6.05–92.19) | 0.010 |
| CANO (ppb) | 6.49 (0.65–10.1) | 7.79 (4.16–14.27) | 5.20 (1.24–12.65) | 0.015 |
Notes: All variables were described as median (95% CI). p_values were based Kruskal–Wallis H-test for continuous variables, ppb: a fractional concentration of part per billion (10−9) or nl/L.
Abbreviations: FENO, fractional exhaled nitric oxide; J’AWNO, bronchial nitric oxide flow; CANO, alveolar concentration of nitric oxide; ppb, part per billion.