Table 3.
Incidence of PH stratified by number of elevated vascular biomarkers measured at cohort entry. Increased number of elevated biomarkers associates with higher incidence of PH during follow-up (HR 1.78). With each increased in the number of biomarkers elevated at cohort entry, the risk of PH increases by 78%.
| Number of Biomarkers at Baseline > Optimal Cutoff | PH Defined as mPAP≥21 | ||
|---|---|---|---|
| No (%) | Yes (%) | Total | |
| 0 | 23 (92) | 2 (8) | 25 |
| 1 | 59 (97) | 2 (3) | 61 |
| 2 | 73 (90) | 8 (10) | 81 |
| 3 | 53 (80) | 13 (20) | 66 |
| 4 | 29 (76) | 9 (24) | 38 |
| 5 | 17 (58) | 12 (42) | 29 |
| Total | 254 | 46 | 300 |