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. 2021 Jun 4;23(6):e24712. doi: 10.2196/24712

Table 2.

Interventions, outcomes, measurements, results, and conclusions of included studies.

Study Interventions Comparators Intervention duration Follow-up duration Outcomes: loneliness scores by measurement stages, mean (SD) Results or findings Conclusion by the authors of the study





Baseline 3 months 4 months 6 months 12 months

Tsai et al (2010) [46] Videoconferencing (using either MSNa messenger or Skype) Regular care 3 months 3 months Intervention group=50.58 (SD 11.16); control group=46.55 (SD 9.07) Intervention group=47.33 (SD 13.50); control group=46.68 (SD 9.08) Not measured Not measured Not measured Loneliness: intervention group mean: baseline 50.58 (SD 11.16), 1 week 49.75 (SD 11.79), and 3 months 47.33 (SD 13.50); control group mean: baseline 46.55 (SD 9.07), 1 week 47.06 (SD 8.75), and 3 months 46.68 (SD 9.08); differences between groups were compared at 3 points (baseline, 1 week, and 3 months) using multiple linear regression of the generalized estimating equations. Unadjusted or fixed effect size of effectiveness of videoconferencing intervention (videoconference vs control): at 1 week was β=−1.21, SE 0.50, χ2=5.9, P=.02 and at 3 months β=−2.84, SE 1.28, χ2=4.9, P=.03 Videoconferencing alleviates depressive symptoms and loneliness in older residents in nursing homes
van der Heide et al (2012) [48] CareTV including Caret duplex video or voice network No control group and no comparator 12 months 12 months Intervention group=5.97 (SD 2.77); no control group Not measured Not measured Not measured Intervention group=4.02 (SD 3.91); no control group Group-level total loneliness: inclusion stage: mean 5.97 (SD 2.77), end of study: mean 4.02 (SD 3.91), P=.001; individual-level total loneliness: total loneliness decreased in 54 out of 85 participants (equally lonely 11, more lonely 20, and less lonely 54 individual participants) CareTV intervention decreased the feeling of loneliness in the participants; however, participants were feeling moderate loneliness at the end of the study
Larsson et al (2016) [50] SIBAsb, that is, social activities via social websites No comparator intervention reported 3 months 34 weeks (exposure for 3 months to each group) Group 1 (I/Cc group)=45.53 (SD 7.41); group 2 (C/Id group)=43.93 (SD 8.61) Group 1 (I/C group)=42.43 (SD 7.44); group 2 (C/I group)=41.93 (SD 8.82) Not measured 3 months after cross over: group 1 (I/C group, no intervention)=42.0 (SD 7.34); group 2 (C/I group, intervention introduced)=39.50 (SD 10.42) Not measured Percentage change between time 2 and time 1: group 1: mean score 0.07% (SD 0.07), P=.003; group 2: mean score: 0.05% (SD 0.09), P=.049; percentage change between time 3 and time 1: group 1: mean score 0.08% (SD 0.08); group 2: mean score 0.09% (SD 0.13); comparison of pre and postintervention scores: group 1, P=.003 and group 2, P=.049 SIBA interventions have the potential to reduce experiences of loneliness in socially vulnerable older adults.
Czaja et al (2018) [45] PRISMe system A notebook with printed content similar to that within the PRISM (intervention) group: included a Lenovo Mini Desktop PC with a keyboard, mouse (or trackball for those who were unable to control a mouse), a 19″ LCDf monitor, the PRISM software app, a printer, and internet 12 months 12 months Intervention (PRISM) group=39.8 (SD 9.7); control (Binderg) group=40.2 (SD 10.3) Not measured Not measured Intervention (PRISM) group=37.8 (SD 9.54); control (Binder) group=40 (SD 10.62) Intervention (PRISM) group=36.9 (SD 9.16); control (Binder) group=38.43 (SD 9.37) Baseline: loneliness PRISM group: mean score 39.8 (SD 9.7); Binder group: mean score 40.2 (SD 10.3), follow-up at 6 months: PRISM group 37.8, Binder group 39.6; follow-up at 12 months: PRISM group 36.9, Binder group 38.3 Technology-based apps such as the PRISM system may enhance social connectivity and reduce loneliness among older adults.
Morton et al (2018) [53] EasyPC—a customized computer platform with a simplified touch-screen interface Care as usual plus regular carer visits 3 months 4 months Intervention (training) group (total of residential and domiciliary groups)=1.92 (SE 0.10, SD 0.73); control group (total of residential and domiciliary groups)=2.08 (SE 0.12, SD 0.80) Not measured Intervention (training) group (total of residential and domiciliary groups)=1.86 (SE 0.10, SD 0.66); control group (total of residential and domiciliary groups)=2.12 (SE 0.11, SD 0.62) Not measured Not measured Loneliness scores mean: intervention (training) group: residential group: time 1=1.95 (SE 0.16), time 2=1.92 (SE 0.16), domiciliary group: time 1=1.89 (SE 0.13), time 2=1.79 (SE 0.13), total time 1=1.92 (SE 0.10), time 2=1.86 (SE 0.10); control group: residential group: time 1=2.13 (SE 0.18), time 2=2.20 (SE 0.17), domiciliary group: time 1=2.02 (SE 0.16), time 2=2.05 (SE 0.15), total time 1=2.08 (SE 0.12) and time 2=2.12 (SE 0.11) Internet access and training can support the self and social connectedness of vulnerable older adults and contribute positively to well-being.
Jarvis et al (2019) [54] Living In Network-Connected Communities WhatsApp group for low-intensity cognitive behavioral therapy Usual care, a separate WhatsApp group (Living In Network-Connected Communities 2) 3 months 4 months Not measured Intervention group=2.31 (SD 1.49); control group=2.47 (SD 2.1) Intervention group=1.38 (SD 1.33); control group=4.0 (SD 1.32) Not measured Not measured Loneliness levels: total=baseline−intervention on time 1−intervention on time 2.; χ2=14.6; P=.001 Low-intensity cognitive behavioral therapy mobile health supported by the social networking platform of WhatsApp (Living In Network-Connected Communities) showed significant improvements in loneliness and maladaptive cognitions.

aMSN: Microsoft Network.

bSIBA: social internet-based activity.

cI/C: intervention/control.

dC/I: control/intervention.

ePRISM: Personal Reminder Information and Social Management.

fLCD: liquid-crystal display.

gBinder refers to a group of participants who received a notebook with printed content similar to the Personal Reminder Information and Social Management System.