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. 2021 Jun 14;14:695–703. doi: 10.2147/PGPM.S314860

Table 3.

The MAF and HWE of Candidate SNPs Between Lung Cancer Cases and Healthy Controls

SNP Gene MAF-Cases MAF-Controls HWE p OR (95% CI) p
rs13098637 MFN1 0.20 0.15 0.87 1.368(1.106–1.691) 0.004*
rs3976523 MFN1 0.36 0.33 0.78 1.138(0.962–1.347) 0.132
rs4240897 MFN2 0.26 0.34 0.93 0.681(0.572–0.812) <0.001*
rs2236058 MFN2 0.45 0.53 0.41 0.718(0.612–0.843) <0.001*
rs879255685 DRP1 0.20 0.18 0.10 1.107(0.904–1.357) 0.325
rs879255689 DRP1 0.20 0.16 0.44 1.348(1.094–1.662) 0.005*

Note: *p < 0.05 indicates statistical significance.

Abbreviations: SNP, single nucleotide polymorphism; MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium.