Table 4.
Genotype Frequency Distributions Between Lung Cancer Cases and Healthy Controls
| SNP | Genotype | Control | Case | OR (95% CI) | p |
|---|---|---|---|---|---|
| rs13098637 | T/T | 430 (71.7%) | 387 (64.5%) | 1 | 0.014* |
| T/C | 157 (26.2%) | 189 (31.5%) | 1.34 (1.04–1.73) | ||
| C/C | 13 (2.2%) | 24 (4%) | 2.04 (1.02–4.06) | ||
| rs3976523 | A/A | 269 (44.8%) | 243 (40.5%) | 1 | 0.300 |
| A/C | 268 (44.7%) | 285 (47.5%) | 1.18 (0.92–1.50) | ||
| C/C | 63 (10.5%) | 72 (12%) | 1.26 (0.86–1.85) | ||
| rs4240897 | G/G | 257 (42.8%) | 321 (53.5%) | 1 | <0.001* |
| G/A | 273 (45.5%) | 242 (40.3%) | 0.71 (0.56–0.90) | ||
| A/A | 70 (11.7%) | 37 (6.2%) | 0.42 (0.27–0.64) | ||
| rs2236058 | C/C | 138 (23%) | 179 (29.8%) | 1 | <0.001* |
| C/G | 289 (48.2%) | 306 (51%) | 0.82 (0.62–1.08) | ||
| G/G | 173 (28.8%) | 115 (19.2%) | 0.52 (0.37–0.71) | ||
| rs879255685 | G/G | 393 (65.5%) | 386 (64.3%) | 1 | 0.140 |
| G/A | 193 (32.2%) | 188 (31.3%) | 0.99 (0.77–1.26) | ||
| A/A | 14 (2.3%) | 26 (4.3%) | 1.91 (0.98–3.72) | ||
| rs879255689 | G/G | 421 (70.2%) | 381 (63.5%) | 1 | 0.013* |
| G/A | 167 (27.8%) | 194 (32.3%) | 1.28 (1.01–1.65) | ||
| A/A | 12 (2%) | 25 (4.2%) | 2.30 (1.14–4.65) |
Note: *p < 0.05 indicates statistical significance.
Abbreviations: SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval.