Skip to main content
. 2021 May 28;297(1):100845. doi: 10.1016/j.jbc.2021.100845

Figure 1.

Figure 1

Dose–response of young 5XFAD mouse model to HSV-1 challenge. Survival curves for 5- to 6-week-old 5XFAD and wild-type littermate (WT) mice challenged via IC injections with 105, 104, or 103 PFUs of 17syn+ strain per mouse (A); or 104, 5 × 103, or 103 PFUs of McKrae strain per mouse (B). 5XFAD and WT littermate mice were caged together in random ratios. Individual plots show independent experiments with number (n) of animals of each genotype indicated. Statistical significance (p) was calculated using the log-rank (Mantel–Cox) test.