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Coimmunostaining for Aβ aggregates and HSV-1 using anti-gD in aged 5XFAD mice. Coimmunostaining for Aβ aggregates (H31L21 antibody, green), HSV-1 virus (anti-gD antibody, red), and nuclei (DAPI, blue) in 10-month-old 5XFAD mice challenged IC with 104 PFUs of McKrae examined at 24 h (n = 5 mice) or 48 h (n = 5 mice) postinoculation. Arrows point at staining of blood vessels.
