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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Biomaterials. 2021 Apr 12;273:120797. doi: 10.1016/j.biomaterials.2021.120797

Figure 5. Stiffness sensing induces gradient of gene expression.

Figure 5.

(A) Number of Differentially Expressed (DE) genes between for pairwise comparisons. (B) Number of genes with p-adjusted value < 0.1 based on DESeq2 algorithm (Log2Fold Change > 0 indicates upregulation towards lower stiffness, Log2Fold Change < 0 indicates upregulation towards higher stiffness). (C) Volcano plot for DE genes between 5 vs 110 kPa conditions. (D) Heatmap of significant genes between 5 vs 110 kPa and 5 vs 25 kPa conditions.