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. 2021 Jun 18;22:458. doi: 10.1186/s12864-021-07793-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Mutation of the 33 top-ranked genes and overall patient survival. A The mutational frequency comparison of the 33 genes in 14 brain cancer studies. B The overall patient survival analysis of 2997 samples from the 14 studies. The dataset abbreviations are The Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC), Glioblastoma (GBM), Memorial Sloan Kettering Institute (MSK), Desmoplastic Infantile Ganglioglioma (DIFG), Low Grade Glioma (LGG), Medulloblastoma (MBL), Pheochromocytoma and Paraganglioma (PCPG), Pilocytic Astrocytoma (PAST)